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Swizerland |
University of Bern |
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Profile
The strategic vision of the
ARTORG Center is to advance healthcare by integrating education, discovery,
innovation and entrepreneurship. The Center supports this effort by
encouraging a new partnership between clinicians, laboratory scientists and
engineers and aims to: cultivate new translational research projects based
on clinical practice needs, identify and support promising biomedical
engineering collaborative research projects, rapidly translate biomedical
engineering research into the clinic by fully utilizing the University of
Bern resources for technology transfer
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Research
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MEDICAL ROBOTICS
ARTORG • Implantation Technology
ISTB • Institute for Surgical Technologies and Biomechanics
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Motivation
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Direct
Acoustical Cochlear Stimulation
> Novel implant generation (Phonak AI)
> Implantation in temporal bone
> Limited surgical approach
> Challenge: Protection of nerves
Approach
1. High-Res Imaging (~0.001mm3)
2. Computer assisted planning
3. High precision tracking
4. Robotic milling guidance
→ High Precision Navigation |
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 Computer Aided Hearing Aid Implantations
for Direct Acoustic Cochlear Stimulation (DACS) Systems
1 - Computer Aided Segmentation
and Planning
2 - Navigation Support for High precision instrument guidance
3 - Robotics guided cavity milling for complex geometries
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High Resolution Imaging
Goal
> Identify combination (Image quality, Resolution) = f ( Radiation )
> Image resolution: 0.001 – 0.002 mm3 / voxel
> Visibility of anatomical details
Result
> Identification of Digital Volume Tomography as suitable imaging
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Computer Assisted Planning
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Goal
> Computer Based Planning
Approach
> Segmentation of inner ear
> Modelling of components
> Planning of intervention
Result
> Intuitive planning tool
> Optimized Planning |
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High Precision Navigation
Problem
> Available navigation approaches are insufficient by factor 10
> Comparison of typical geometric errors

Approach
> Microscale Optical Tracking Using Frequency Domain Multiplexing*
> Work volume: 30 cm3
> Resolution: 4 μm at 1 kHz
> Collaboration with CMU
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Robot Milling Guidance
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Goal
> Precise instrument manipulation
platform
Approach
> Self Development & Manufacturing
Results
> 5DoF Precision Manipulator
Outlook
> Force Feedback Control
> Interface to Navigation |
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Research Units
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Artificial Hearing Research
The ARTORG Center for Artificial Hearing Research which
has been established in September 2008 is part of the Artificial Organs (ARTORG)
Center for Biomedical Engineering Research of the University of Bern.
The sense of hearing fulfils an important function in interpersonal
relationships, but also helps to orientate and to alerts of danger. The
disease of hearing loss is quite often and goes from a light loss up to
complete deafness. The ARTORG Center for Artificial Hearing investigates in
implantable hearing systems and theirs surgical and audiological procedures.
The Artificial Hearing Research Group operates in a network consisting of
engineers, surgeons, audiologists and industrial partners. The Artificial
Hearing Research as a part of the departement of ENT head and neck surgery
of the Inselspital has a large experience in hearing rehablitation i.e.
otological microsurgery, conventional hearing systems, semi- and fully
implantable hearing systems and cochlear implants. Based on this large
experience the Artificial Hearing Research Group focuses on clinical driven
research in implantable hearing systems. The research group of artificial
hearing is at any given point interested in offering academic work
opportunities to highly motivated and encouraged individuals at all levels
(i.e. Master Students, PhD students, PostDocs, Group leaders etc.). We are
always looking forward to receiving applications from interested persons
with a broad background in engineering, computer science, physics and
mathematics. Always feel free to contact us.
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Center Comp. Aided Surgery
The ARTORG Center for Computer Aided Surgery (CCAS) is a
joint technological and clinical research effort within the ARTORG Center of
the University of Bern and the Inselspital (Medical Faculty of the
University of Bern). CCAS connects technological expertise in the areas of
computer aided surgery, diagnosis, medical image processing and smart
instruments with clinical problems and motivations. The bandwith of our
research activities ranges from answering novel clinical challenges to
improving existing approaches and medical technology with competences from a
purely algorithmic developments across component and systems development all
the way to clinical validation (through our clinical network). CCAS
envisions to support society and its healthcare system for the challenges to
come (demographic, economic, socio-cultural) by the enhancement and
integration of novel technology, improving its availability for patients and
indications and demonstrating its clinical benefit respectively.
The center aims on creating a powerful network of scientists with
engineering and medical backgrounds with a awareness for the possibilities
of one anothers side: Engineers with expertise on clinical problems,
workflows and methodologies as well as clinicians with understanding of
technological approaches, possibilities. Together, both sides can and will
create novel diagnosis and therapy solutions with real clinical impact. CCAS
is co-directed by two experts from the scientific and clinical disciplines,
respectively.
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Computational Bioengineering
The Computational Bioengineering Group tackles challenges
in basic and applied medical research with modern computational simulation
tools. Rather than focusing on the computational methods themselves, we are
concerned with their appropriate application to resolve practical and
fundamental clinical questions. Numerical methods are combined with
experimental and clinical research in order to improve the quality and
extend the validity of our models.
Together with our collaborators we constitute a strong team covering a wide
spectrum of research topics ranging from direct support of surgical patient
treatment to basic cell research. Besides our core expertise in applying
finite element analysis to study skeletal biomechanics, we are seeking to
improve surgical planning by developing and applying refined numerical
techniques into the field of computer aided surgery. Another important
research focus of the group is modeling the metabolic activity at the organ
and tissue level and its alteration by external stimuli.
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Diabetes Technology
The ARTORG Diabetes Technology Research Group (DTRG)
which has been established in November 2008 is part of the Artificial Organs
(ARTORG) Center for Biomedical Engineering Research of the University of
Bern.
DTRG incorporated into the Faculty of Medicine of the University of Bern and
the Inselspital (University Hospital of Bern) brings together people from
medicine, engineering and physical science in order to conduct research on
the application of technology in diabetes mellitus. DTRG is mainly active in
the following areas:
- Closed loop artificial pancreas
- Simulation, modeling and control of complex, non-linear metabolic
systems
- Decision support systems for management of glucose profile
- Computational tools for analysis of data related to diabetes
mellitus
- Advanced tools for the identification of interactions in the
development of complex disease phenotypes, like chronic metabolic
disorders
- Assessment of glucose monitoring devices and insulin delivery
systems
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Spine Research Center
The ARTORG Spine Research Center (SRC) is a collaborative
research organization operating under the umbrella of the ARTORG Center of
the University of Bern. The SRC draws together the expertise of researchers
from the Institute for Surgical Technology and Biomechanics (ISTB) and the
Spine Service of the Department of Orthopaedic Surgery (Inselspital),
performing basic and applied biomedical research and clinical research to
seek new solutions for the treatment of spinal disorders. The strategic
vision of the Spine Research Center is to advance spinal care by integrating
education, discovery, application and evaluation, with the patient firmly in
the foreground.
The SRC is co-directed by three experts from the scientific and clinical
disciplines, respectively. The SRC builds on the historical strengths of
clinically-driven orthopaedic research at the University of Bern, with
nearly two decades of experience as recognized leaders in the field of spine
biomechanics research and innovators in the clinical treatment of spinal
disorders, and has well- established collaborative links to internal and
external institutes covering the broad spectrum of multi-disciplinary
research activities.The SRC is strongly integrated with the medical
technology industry network in Switzerland, ensuring a direct path to the
realization of our research goals.
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Ophthalmic Technology Group
The Ophthalmic Technology Group is dedicated to the
development of innovative surgical and diagnostic instruments and techniques
in the area of ophthalmology. The novel engineering solutions should allow
for an increased surgical precision, while at the same time diminish the
risks for patients and reduce the costs for the intervention. We are focused
on projects that are clinically relevant and we are committed to advance the
project development to a state were a potential clinical benefit can be
assessed. The successful combination of applied research and development on
one side and clinical implementation on the other represents the main
challenge of our group.
The Ophthalmic Technology Group consists of a multi-disciplinary team of
engineers and clinicians. Our core competencies are in mechatronic systems
design, signal processing, computer vision and computer graphics.
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Cardiovascular Engineering
Switzerland 1977, Dr. Andreas Grüntzig performed the
worldwide first balloon dilatation of a coronary artery to treat coronary
artery disease. He used a balloon catheter that was developed in close
collaboration with engineers and clinicians. Our mission is to carry on this
tradition and spirit leading to the development of innovative cardiovascular
devices and treatment techniques.
ARTORG Cardiovascular Engineering (ACE) is a joint technological-clinical
research organization that is part of the newly founded Artificial Organ (ARTORG)
Center for Biomedical Engineering Research at the University of Bern. The
clinical partners of ACE are found in the Departments of Cardiovascular
Surgery and Cardiology (Inselspital, University Hospital Bern) and the
Medical Faculty of the University of Bern. ACE converges expertise in
biomedical engineering research, clinical research and clinical medicine in
search of novel solutions for the diagnostic and therapeutic management of
cardiovascular diseases. With the patient in the focus, our dedicated vision
is to improve cardiovascular care by education, development, application and
evaluation. To achieve this, joint ventures are formed and services rendered
to lead to continuous translation of new technologies to clinical practice.
ACE is co-directed by two experienced researchers with strong technological
and clinical background, respectively, and has well established
collaborative links to internal and external institutes covering the broad
spectrum of multi-disciplinary research activities. ACE is well integrated
into the medical technology industry network worldwide and in Switzerland,
ensuring a direct path to the realization of our research goals.
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